| First Author | Sadoul R | Year | 1991 |
| Journal | Biochim Biophys Acta | Volume | 1089 |
| Issue | 2 | Pages | 259-61 |
| PubMed ID | 1675873 | Mgi Jnum | J:43582 |
| Mgi Id | MGI:1098069 | Doi | 10.1016/0167-4781(91)90020-m |
| Citation | Sadoul R, et al. (1991) Sequence analysis of the homeobox-containing exon of the murine Hox-4.3 homeogene. Biochim Biophys Acta 1089(2):259-61 |
| abstractText | A homeobox-containing gene * was detected by Southern analysis of a cosmid spanning a region of the murine HOX-4 complex between Hox-4.4 (Hox-5.2) and Hox-4.2 (Hox-5.1) with a probe derived from the Hox-4.2 homeobox. The sequence of a cross-hybridizing region revealed an open reading frame encoding an Antennapedia (Antp) class homeodomain highly homologous to the products of human HOX4C (Hox-5.4/HOX4E), mouse Hox-3.1 and Hox-2.4. This, together with strong conservation of sequences 3' to the homoebox, indicates that we have cloned the murine Hox-4.3 gene. No other homeobox sequences were detected in this screen suggesting that the HOX-4 complex lacks paralogous genes represented in the equivalent regions of other HOX loci. |
