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Publication : Estrogen receptor-beta mRNA variants in human and murine tissues.

First Author  Lu B Year  1998
Journal  Mol Cell Endocrinol Volume  138
Issue  1-2 Pages  199-203
PubMed ID  9685228 Mgi Jnum  J:48169
Mgi Id  MGI:1266904 Doi  10.1016/s0303-7207(98)00050-1
Citation  Lu B, et al. (1998) Estrogen receptor-beta mRNA variants in human and murine tissues. Mol Cell Endocrinol 138(1-2):199-203
abstractText  Estrogen receptor (ER)-beta mRNA splice variants have been identified in human breast tumors as well as normal human and mouse ovarian, uterine and mammary tissues. In both species transcripts deleted in exons 5 or 6, or 5 + 6 have been characterized by RT-PCR followed by cloning and sequencing. In mouse tissues an ER-beta transcript containing 54 nucleotides inserted in frame between exons 5 and 6 was identified. Interestingly, no equivalent of the mouse inserted transcript was detected in any of the four human tissues analyzed.
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