| First Author | Incerti B | Year | 1994 |
| Journal | Biochim Biophys Acta | Volume | 1222 |
| Issue | 1 | Pages | 125-8 |
| PubMed ID | 8186260 | Mgi Jnum | J:18459 |
| Mgi Id | MGI:67230 | Doi | 10.1016/0167-4889(94)90034-5 |
| Citation | Incerti B, et al. (1994) Structure of the mouse growth/differentiation factor 9 gene. Biochim Biophys Acta 1222(1):125-8 |
| abstractText | Using a mouse GDF-9 cDNA as a probe, over 20 kb of sequence encompassing the GDF-9 gene was isolated from a mouse 129SvEv genomic library. Sequence analysis of the exons, exon-intron boundaries, and 5'- and 3'-non-translated regions was used to establish the structure of the mouse GDF-9 gene. The GDF-9 gene is encoded by two exons separated by a 2.9 kb intron. Multiple putative transcription start sites are detected between 31 and 57 bp upstream of the start site of translation and a putative polyadenylation signal lies 342 bp 3' of the end of translation. Knowledge of the GDF-9 gene structure will enable us to further understand the role of GDF-9 in ovarian physiology and development. |
