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Publication : Casein kinase 1 delta (CK1delta) interacts with the SNARE associated protein snapin.

First Author  Wolff S Year  2006
Journal  FEBS Lett Volume  580
Issue  27 Pages  6477-84
PubMed ID  17101137 Mgi Jnum  J:117718
Mgi Id  MGI:3697290 Doi  10.1016/j.febslet.2006.10.068
Citation  Wolff S, et al. (2006) Casein kinase 1 delta (CK1delta) interacts with the SNARE associated protein snapin. FEBS Lett 580(27):6477-84
abstractText  In this study we identified snapin as an interaction partner of the CK1 isoform delta (CK1delta) in the yeast two-hybrid system and localized the interacting domains of both proteins. The interaction of CK1delta with snapin was confirmed by co-immunoprecipitation. Snapin was phosphorylated by CK1delta in vitro. Both proteins localized in close proximity in the perinuclear region, wherein snapin was found to associate with membranes of the Golgi apparatus. The identification of snapin as a new substrate of CK1delta points towards a possible function for CK1delta in modulating snapin specific functions.
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