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Publication : Identification and chromosomal mapping of a third mouse runt-like locus.

First Author  Calabi F Year  1995
Journal  Genomics Volume  26
Issue  3 Pages  607-10
PubMed ID  7607689 Mgi Jnum  J:25235
Mgi Id  MGI:72962 Doi  10.1016/0888-7543(95)80184-n
Citation  Calabi F, et al. (1995) Identification and chromosomal mapping of a third mouse runt-like locus. Genomics 26(3):607-10
abstractText  The Drosophila runt gene, which controls early events in embryogenesis, has been shown to have homologues in human and mouse. The human gene on 21q22 is involved in the t(8;21) associated with acute myeloid leukemia. Two mouse runt-like loci encoding DNA-binding proteins have been identified. We report here the isolation and partial sequence of a molecular clone of a third mouse runt-like locus. By using a panel of somatic cell hybrids and interspecific backcross mice, we map the novel locus to the telomeric region of mouse chromosome 4.
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