First Author | Calabi F | Year | 1995 |
Journal | Genomics | Volume | 26 |
Issue | 3 | Pages | 607-10 |
PubMed ID | 7607689 | Mgi Jnum | J:25235 |
Mgi Id | MGI:72962 | Doi | 10.1016/0888-7543(95)80184-n |
Citation | Calabi F, et al. (1995) Identification and chromosomal mapping of a third mouse runt-like locus. Genomics 26(3):607-10 |
abstractText | The Drosophila runt gene, which controls early events in embryogenesis, has been shown to have homologues in human and mouse. The human gene on 21q22 is involved in the t(8;21) associated with acute myeloid leukemia. Two mouse runt-like loci encoding DNA-binding proteins have been identified. We report here the isolation and partial sequence of a molecular clone of a third mouse runt-like locus. By using a panel of somatic cell hybrids and interspecific backcross mice, we map the novel locus to the telomeric region of mouse chromosome 4. |