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Publication : Nucleotide sequence of the murine prothymosin alpha cDNA and its deduced primary and secondary protein structure.

First Author  Schmidt G Year  1991
Journal  Biochim Biophys Acta Volume  1088
Issue  3 Pages  442-4
PubMed ID  2015308 Mgi Jnum  J:11117
Mgi Id  MGI:59559 Doi  10.1016/0167-4781(91)90141-8
Citation  Schmidt G, et al. (1991) Nucleotide sequence of the murine prothymosin alpha cDNA and its deduced primary and secondary protein structure. Biochim Biophys Acta 1088(3):442-4
abstractText  Searching for proliferation-related and cell cycle phase-specific genes we detected a full-length cDNA for the murine prothymosin alpha mRNA which was sequenced on the DNA level. The amino acid sequence deduced from the nucleotide sequence shows a high degree of positional identities with prothymosin alpha from man and rat. However, the minor differences in the primary structures largely influence predictions for the secondary structures of prothymosin alpha from different species. These differences in the secondary structure could explain the differences of activity of prothymosin alpha from different origin in immuno-protection assays.
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