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Publication : Cloning and sequencing of mouse glutaredoxin (grx) cDNA.

First Author  Miranda-Vizuete A Year  1999
Journal  DNA Seq Volume  10
Issue  3 Pages  179-82
PubMed ID  10647820 Mgi Jnum  J:59632
Mgi Id  MGI:1352002 Doi  10.3109/10425179909033944
Citation  Miranda-Vizuete A, et al. (1999) Cloning and sequencing of mouse glutaredoxin (grx) cDNA. DNA Seq 10(3):179-82
abstractText  Glutaredoxins are small proteins (12 kDa) with a conserved active sequence Cys-Pro-Tyr(-Phe)-Cys that catalyse GSH-disulfide oxidoreduction reactions in the presence of NADPH and glutathione reductase. Many mammalian glutaredoxins have been characterized and human and pig cDNA sequence determined. However, no mouse glutaredoxin cDNA or protein sequence has yet been reported. We have cloned a cDNA from a mouse liver library that encodes the putative mouse glutaredoxin homologue. The deduced polypeptide sequence encodes a 107 amino acid protein displaying a high degree of homology with other members of the glutaredoxin family.
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