| First Author | Boer PH | Year | 1987 |
| Journal | Mol Cell Biol | Volume | 7 |
| Issue | 9 | Pages | 3107-12 |
| PubMed ID | 2823118 | Mgi Jnum | J:15352 |
| Mgi Id | MGI:63478 | Doi | 10.1128/mcb.7.9.3107 |
| Citation | Boer PH, et al. (1987) The testis-specific phosphoglycerate kinase gene pgk-2 is a recruited retroposon. Mol Cell Biol 7(9):3107-12 |
| abstractText | In both humans and mice, two genes encode phosphoglycerate kinase, a key enzyme in the glycolytic pathway. The pgk-1 gene is expressed in all somatic cells, is located on the X chromosome, and contains 10 introns. The pgk-2 gene is expressed only in sperm cells, is located on an autosome, and has no introns. The nucleotide sequence of the pgk-2 gene suggests that it arose from pgk-1 more than 100 million years ago by RNA-mediated gene duplication. The pgk-2 gene may, then, be a transcribed retroposon. Thus, gene duplication by retroposition may have been used as a mechanism for evolutionary diversification. |
