| First Author | Hamaguchi Y | Year | 1991 |
| Journal | Adv Exp Med Biol | Volume | 292 |
| Pages | 177-86 | PubMed ID | 1950768 |
| Mgi Jnum | J:609 | Mgi Id | MGI:49145 |
| Doi | 10.1007/978-1-4684-5943-2_20 | Citation | Hamaguchi Y, et al. (1991) Cloning and characterization of a protein binding to the J kappa recombination signal sequence of immunoglobulin genes. Adv Exp Med Biol 292:177-86 |
| abstractText | A protein with molecular weight of 60,000 that binds to the recombination signal sequence (RS) of the immunoglobulin J kappa segment was purified from the nuclear extract of a murine pre B cell line 38B9. This binding protein was found in lymphoid cell lines but not in non-lymphoid cell lines. The Kd value of the J kappa RS binding protein to the J kappa RS was 1 nM. The cDNA clone (RBP-2) was isolated based on partial amino-acid sequence of this protein. This cDNA encodes 526 amino-acid residues, and its sequence does not show extensive overall homology with any known proteins, but displays an interesting homology to a 40-residue region that is conserved among a subset of site specific recombinase (integrase family). |
