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Publication : A growth arrest-specific (gas) gene codes for a membrane protein.

First Author  Manfioletti G Year  1990
Journal  Mol Cell Biol Volume  10
Issue  6 Pages  2924-30
PubMed ID  1692961 Mgi Jnum  J:42516
Mgi Id  MGI:1099759 Doi  10.1128/mcb.10.6.2924
Citation  Manfioletti G, et al. (1990) A growth arrest-specific (gas) gene codes for a membrane protein. Mol Cell Biol 10(6):2924-30
abstractText  A set of growth arrest-specific (gas) genes whose expression is negatively regulated by serum has recently been identified. We report on the detailed analysis of one of these genes (gas3). The kinetics of regulation by the presence and absence of serum were investigated, and it was found that this gene is regulated at the post-transcriptional level. The encoded protein deduced from the nucleotide sequence showed some similarity to a mitochondrial oxyreductase, and in vitro translation established that the protein product is a transmembrane glycoprotein.
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