| First Author | Akagi J | Year | 1988 |
| Journal | Biochem Biophys Res Commun | Volume | 157 |
| Issue | 2 | Pages | 548-57 |
| PubMed ID | 3202867 | Mgi Jnum | J:39942 |
| Mgi Id | MGI:87764 | Doi | 10.1016/s0006-291x(88)80284-5 |
| Citation | Akagi J, et al. (1988) Messenger RNA expressed in mouse teratocarcinoma stem cells and down-regulated by a tumor-promoting phorbol ester codes for a novel transmembrane protein. Biochem Biophys Res Commun 157(2):548-57 |
| abstractText | Cloning and sequence analysis of a DNA complementary to the mRNA expressed in undifferentiated mouse F9 teratocarcinoma stem cells but disappearing rapidly after treatment with a tumor-promoting phorbol ester revealed it to be a 1.9 kilobase pairs-long cDNA encoding a protein of 323 amino acid residues. Computer-assisted analyses of the deduced amino acid sequence indicated that this protein contains a typical hydrophobic signal peptide consisting of 33 amino acid residues and six putative membrane-spanning segments. The deduced amino acid sequence, as a whole, bears no significant sequence homology to any previously described protein. |
