| description | Viral protein involved in evading host innate and adaptive immune responses, allowing optimized viral replication, propagation, or persistence in the host. The protein allows viruses to avoid/escape immune detection or neutralize/inactivate the host immune defenses to ensure virus survival within its host. The innate immune system is a non-specific defense system found in all cellular organisms. In metazoans and plants, it includes the intracellular pattern recognition receptors (PRRs) that detect pathogen-associated molecular patterns (PAMPs). In plants and invertebrates, it includes the RNA interference (RNAi) system. Plants also have effector-triggered immunity (ETI). In metazoans, it includes the cell-dependent mechanisms (e.g. phagocytes) or secreted factors. Bacteria and archaea have an innate immune system relying on various systems (e.g. the restriction-modification system, Pycsar). The adaptive (or acquired) immune system is a specific defense. In vertebrates, it is mediated by T and B lymphocytes expressing specific receptors. Bacteria and archaea have adaptive immunity, the CRISPR-Cas system |
Ontology Term --> All ancestors
Ontology Term --> All descendants
Ontology Term --> Direct children
Ontology Term --> Direct parents
