First Author | Kwak JW | Year | 1996 |
Journal | Gene | Volume | 173 |
Issue | 2 | Pages | 257-9 |
PubMed ID | 8964510 | Mgi Jnum | J:35400 |
Mgi Id | MGI:82849 | Doi | 10.1016/0378-1119(96)00077-7 |
Citation | Kwak JW, et al. (1996) Cloning and characterization of cDNAs coding for heavy and light chains of a monoclonal antibody (MabA34) specific for human plasma apolipoprotein A-I. Gene 173(2):257-9 |
abstractText | We have determined the nucleotide (nt) sequences encoding the heavy (H)- and light (L)-chains of the Fab fragment of a murine monoclonal antibody, MabA34 (gamma1, kappa), which is specific for human plasma apolipoprotein A-I of high-density lipoproteins. The variable (V) regions of the H- and L-chains were revealed to be members of mouse H-chain subgroup II(A) and kappa L-chain subgroup II, respectively. A few unusual amino acids in the V region of the H-chain, and nt residues probably introduced by somatic mutations from germline genes were also identified. |