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Publication : New PKCdelta family members, PKCdeltaIV, deltaV, deltaVI, and deltaVII are specifically expressed in mouse testis.

First Author  Kawaguchi T Year  2006
Journal  FEBS Lett Volume  580
Issue  10 Pages  2458-64
PubMed ID  16638571 Mgi Jnum  J:108430
Mgi Id  MGI:3624043 Doi  10.1016/j.febslet.2006.03.084
Citation  Kawaguchi T, et al. (2006) New PKCdelta family members, PKCdeltaIV, deltaV, deltaVI, and deltaVII are specifically expressed in mouse testis. FEBS Lett 580(10):2458-64
abstractText  We isolated and characterized four new PKCdelta isoforms, PKCdeltaIV, deltaV, deltaVI, and deltaVII, specifically expressed in the mouse testis. These isoforms possess neither V1 nor C2-like domains. Moreover, PKCdeltaVI and deltaVII have a different last exon as their V5 domain. The transcription of PKCdeltaIV, deltaV, deltaVI, and deltaVII is initiated from the same site in the upstream region of exon4 of the PKCdelta gene. They are expressed exclusively in the testis in an age-dependent manner. PKCdeltaIV and deltaV are expressed in spermatids with sperm maturation stage-specific manner, and that PKCdeltaVI and deltaVII are expressed in spermatogonia and spermatocytes.
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