First Author | de Murcia G | Year | 1994 |
Journal | Trends Biochem Sci | Volume | 19 |
Issue | 4 | Pages | 172-6 |
PubMed ID | 8016868 | Mgi Jnum | J:53844 |
Mgi Id | MGI:1334829 | Doi | 10.1016/0968-0004(94)90280-1 |
Citation | de Murcia G, et al. (1994) Poly(ADP-ribose) polymerase: a molecular nick-sensor [published erratum appears in Trends Biochem Sci 1994 Jun;19(6):250]. Trends Biochem Sci 19(4):172-6 |
abstractText | Poly(ADP-ribose) polymerase (PARP) participates in the intricate network of systems developed by the eukaryotic cell to cope with the numerous environmental and endogenous genotoxic agents. Cloning of the PARP gene has allowed the development of genetic and molecular approaches to elucidate the structure and function of this abundant and highly conserved enzyme. |