Primary Identifier | IPR012092 | Type | Family |
Short Name | DNA_glyclase/AP_lyase_Ogg |
description | This entry represents bifunctional, thermostable 8-oxoguanine DNA glycosylase/DNA lyase enzymes (OGG or OG glycosylases), which are involved in base excision repair of DNAdamaged by oxidation or by mutagenic agents []. Most damage to bases in DNA is repaired by the base excision repair pathway []. These enzymes have both DNA glycosylase activity () and AP lyase activity (). OGG1 enzymes are active only towards the removal of 8-oxoguanine []. |