Primary Identifier | IPR032919 | Type | Family |
Short Name | PDZ-RhoGEF |
description | Rho guanine nucleotide exchange factor 11, also known as PDZ-RhoGEF, is a guanine nucleotide exchange factor (GEFs) for Rho GTPase that plays critical roles in signalling []. PDZ-RhoGEF uses its PDZ domains to bind class B plexins and plays a role in axon guidance [, ]. It is involved in neurotrophin-induced neurite outgrowth []. |