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Protein Domain : Rho guanine nucleotide exchange factor 11

Primary Identifier  IPR032919 Type  Family
Short Name  PDZ-RhoGEF
description  Rho guanine nucleotide exchange factor 11, also known as PDZ-RhoGEF, is a guanine nucleotide exchange factor (GEFs) for Rho GTPase that plays critical roles in signalling []. PDZ-RhoGEF uses its PDZ domains to bind class B plexins and plays a role in axon guidance [, ]. It is involved in neurotrophin-induced neurite outgrowth [].

0 Child Features

0 Parent Features

11 Protein Domain Regions