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Protein Domain : Rho guanine nucleotide exchange factor 10/17

Primary Identifier  IPR039919 Type  Family
Short Name  ARHGEF10/ARHGEF17
description  This entry includes Rho guanine nucleotide exchange factors 10 and 17.ARHGEF10 is a Rho guanine nucleotide exchange factor that may play a role in developmental myelination of peripheral nerves []. It was found to regulate mitotic spindle formation and play a role in the regulation of the cell division cycle [].ARHGEF17 is a guanine nucleotide exchange for for RhoA GTPases; it contains a Dbl homology (DH) domain but lacks the typical pleckstrin homology domain [].

2 Child Features

0 Parent Features

14 Protein Domain Regions