Primary Identifier | IPR039130 | Type | Family |
Short Name | INCENP |
description | Inner centromere protein (INCENP) is a component of the chromosomal passenger complex (CPC), which is an important regulator of mitosis. CPC ensures correct alignment and segregation of chromosomes at the centromere. INCENT interacts with several other CPC subunits [, , ]and it activates subunits AURKB and AURKC []; it also interacts with the tubulin beta chain []. Two paralogues exist in Xenopus named INCEP A and B. |