Primary Identifier | IPR008905 | Type | Domain |
Short Name | EIF3C_N_dom |
description | The largest of the mammalian translation initiation factors, eIF3, consists of at least eight subunits ranging in mass from 35 to 170kDa. eIF3 binds to the 40 S ribosome in an early step of translation initiation and promotes the binding of methionyl-tRNAi and mRNA []. The N-terminal domain of eukaryotic translation initiation factor 3 subunit C mediates eIF3 binding to eIF1 and eIF5 []. |