Primary Identifier | IPR039106 | Type | Family |
Short Name | INAVA |
description | Innate immunity activator protein (INAVA) is required for optimal MAPK and NF-kappaB activation, cytokine secretion, and intracellular bacterial clearance. Genetic variations in INAVA are associated with an increased risk of inflammatory bowel disease []. Homologues are known from chordates. |