Primary Identifier | IPR033546 | Type | Family |
Short Name | ZBED3 |
description | Zinc-finger BED domain-containing protein 3 (Zbed3) is a zinc finger protein that binds to axin and activates the Wnt/beta-catenin signalling. Interaction with axin is important for Zbed3 to inhibit beta-catenin phosphorylation, hence inhibiting beta-catenin degradation []. Zbed3 has been associated with insulin resistance and type 2 diabetes mellitus in humans [, ]. |