|  Help  |  About  |  Contact Us

Protein Domain : Zinc finger BED domain-containing protein 3

Primary Identifier  IPR033546 Type  Family
Short Name  ZBED3
description  Zinc-finger BED domain-containing protein 3 (Zbed3) is a zinc finger protein that binds to axin and activates the Wnt/beta-catenin signalling. Interaction with axin is important for Zbed3 to inhibit beta-catenin phosphorylation, hence inhibiting beta-catenin degradation []. Zbed3 has been associated with insulin resistance and type 2 diabetes mellitus in humans [, ].

0 Child Features

1 Parent Features

4 Protein Domain Regions