Primary Identifier | IPR018501 | Type | Domain |
Short Name | DDT_dom |
description | The DDT has been named after the better characterised DNA-binding homeobox-containing proteins and the Different Transcription and chromatin remodellingfactors in which it is found. It is a domain of about 60 amino acids which isexclusively associated with nuclear domains like AT-Hook,PHD finger, methyl-CpG-binding domain, bromodomain and DNA-binding homeodomain.The DDT domain is characterised by a number of conserved aromatic and chargedresidues and is predicted to consist of three alpha helices. A DNA-bindingfunction for the DDT domain has been proposed []. |