Primary Identifier | IPR031318 | Type | Family |
Short Name | OPI10 |
description | OPI10 family members include protein Hikeshi from vertebrates and protein Opi10 from yeasts. Hikeshi protein acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress; it acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus [].Budding yeast Opi10 is a repressor of the phospholipid biosynthetic genes and specifically binds PA in the endoplasmic reticulum []. |