| Primary Identifier | IPR031311 | Type | Conserved_site |
| Short Name | CHIT_BIND_RR_consensus |
| description | This entry represents the 35-36 amino acid motif known as the R&R consensus. This is a conserved region found in insect cuticular proteins []. Insect cuticle is composed of proteins and chitin. The cuticular proteins seem to be specific to the type of cuticle (flexible or stiff) that occur at stages of the insect development. The proteins found in the flexible cuticle of larva and pupa of different insects share a conserved C-terminal section []; such a region is also found in the soft endocuticle of adults insects []as well as in other cuticular proteins including in arachnids []. This conserved motifof 35-36 amino acids is known as the R&R consensus since it was firstrecognised by Rebers and Riddiford. N-terminal to the consensus is a region ofhydrophilic amino acids. The two regions together have been called theextended R&R consensus, and form an approximately 70 amino acids chitin-binding domain[, ]. |
