| Primary Identifier | IPR018396 | Type | Family |
| Short Name | LAPTM_4A/5 |
| description | The lysosome associated protein transmembrane (LAPTM) family is comprised of three members: LAPTM5, LAPTM4a and LAPTM4b; they are lysosome-associated transmembrane proteins, found in mammals, insects and nematodes.This entry represents LAPTM4 alpha (LAPTM4A) and LAPTM45. LAPTM4A regulates the intracellular compartmentalisation of amphipathic solutes and possibly the sensitivity of cells toward anthracyclines, antibiotics, ionophores, nucleobases and organic cations [, ]. LAPTM5 may have functional role during embryogenesis and in adult hematopoietic cells []. |
