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Protein Domain : Nkap domain containing 1

Primary Identifier  IPR043407 Type  Family
Short Name  Nkap_D1
description  NF-kappa-B-activating protein (Nkap) is a highly conserved protein which functions as a transcriptional repressor on Notch target genes. It is required for T cell development and acquisition of functional competency [, , ]. It also plays a role in RNA splicing and processing involved in transcriptional repression, maintenance and survival of adult haematopoietic stem cells.Nkap is divided into three domains, an N-terminal domain containing RS repeats, a highly basic middle domain and the C-terminal domain () [, ].This entry represents uncharacterised proteins that contain Nkap domain 1.

0 Child Features

0 Parent Features

5 Protein Domain Regions