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Protein Domain : Linker for activation of T-cells family member 2

Primary Identifier  IPR031428 Type  Family
Short Name  LAT2
description  The adaptor protein linker activator of T-cells 2 (LAT2), also called non-T-cell activation linker (NTAL), linker activator for B-cells (LAB) or Williams Beuren Syndrome critical region 5 (WBSCR5), is expressed in various myeloid and lymphoid cells []. Given the wide expression pattern, it may modulate signalling in most types of leukocytes []. It has been shown to be involved in immunoreceptor signaling [], B cell activation [], negative regulation of T cell activation [], and regulation of mast cell physiology [].

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0 Parent Features

9 Protein Domain Regions