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Protein Domain : Kinetochore assembly subunit CENP-C, N-terminal domain

Primary Identifier  IPR028052 Type  Domain
Short Name  CENP-C_N_dom
description  CENP-C is a vertebrate family that forms a core component of the centromeric chromatin. On depletion of CENP-C, proper formation of both centromeres and kinetochores is prevented. In kinetochores, the KMN (KNL1/Mis12/Ndc80) network regulates kinetochore microtubule binding []. The N-terminal of CENP-C is necessary for recruitment of some but not all components of the Mis12 complex to centromeres [, ].

0 Child Features

0 Parent Features

8 Protein Domain Regions