Primary Identifier | IPR004123 | Type | Family |
Short Name | Dim1 |
description | This entry represents fission yeast Dim1 and its homologues, including Dib1 from budding yeasts, YLS8 from plants and TXNL4 from animals. Dim1 was originally identified as a mitosis protein []. Later, it was found to interact with spliceosome component Prp6, which is involved in pre-mRNA splicing []. Dim1 may act at the level of mRNA, which impacts the functioning of the APC/C, a critical complex in controlling mitotic progression [].It's worth noting that although the Dim proteins exhibit a thioredoxin-like fold, they lack the disulfide bond required for the thioredoxin redox activity []. |