| Primary Identifier | IPR031745 | Type | Domain |
| Short Name | Vps53_C |
| description | This entry represents the C-terminal domain of fungal vacuolar protein sorting-associated protein 53 (Vps53), a component of the Golgi-associated retrograde complex (GARP). Budding yeast Vps53 is involved in retrograde transport from early and late endosomes to late Golgi by linking the vesicle through the t-SNARE Tgl1 to the Golgi, leading to the membrane fusion between late Golgi and endosomal vesicles [, ]. This domain has a fold consisting of an α-helical bundle known as the CATCHR fold (complexes associated with tethering containing helical rods) which is shared by proteins of other tethering complexes, namely exocyst, COG and Dsl1 [, ]. |
