Primary Identifier | IPR030228 | Type | Family |
Short Name | Gpn3 |
description | GPN-loop GTPase 3 (Gpn3) belongs to the GPN-loop GTPase family []. Budding yeast Gpn3 plays a role in biogenesis of RNA pol II and polIII []and is involved in sister chromatid cohesion []. Its human homologue, Parcs (pro-apoptotic protein is required for cell survival), is a dual regulator of cell proliferation and Apaf-1 function []. Parcs is also required for the nuclear accumulation of RNA polymerase II []. |