Primary Identifier | IPR028132 | Type | Family |
Short Name | Vasohibin-1 |
description | Tubulinyl-Tyr carboxypeptidase 1 (also known as vasohibin-1, VASH1) regulates microtubule function by removing a C-terminal tyrosine residue from alpha-tubulin []. VASH1 is an angiogenesis inhibitor. It inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis []. VASH1 is predominantly expressed in endothelial cells and it is induced by vascular endothelial growth factor (VEGF) and fibroblast growth factor 2 (FGF-2) []. |