Primary Identifier | IPR018798 | Type | Family |
Short Name | MVB12A/B |
description | MVB12A (also known as CFBP) and MVB12B are subunits of the ESCRT-I complex, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle [, ]. MVB12A plays a key role in the ligand-mediated internalization and down-regulation of the EGF receptor []. |