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Protein Domain : Multivesicular body subunit 12

Primary Identifier  IPR018798 Type  Family
Short Name  MVB12A/B
description  MVB12A (also known as CFBP) and MVB12B are subunits of the ESCRT-I complex, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle [, ]. MVB12A plays a key role in the ligand-mediated internalization and down-regulation of the EGF receptor [].

2 Child Features

0 Parent Features

7 Protein Domain Regions