| Primary Identifier | IPR043566 | Type | Family |
| Short Name | Rabphilin/DOC2/Noc2 |
| description | This entry includes Rabphilin and Doc2. Rabphilin and Doc2s share highly homologous tandem C2 domains, although their N-terminal structures are completely different: Rabphilin contains an N-terminal Rab-binding domain (RBD), whereas Doc2 contains an N-terminal Munc13-1-interacting domain (MID) []. This entry also includes Noc2 (also known as Rabphilin-3A-like protein), which is a potential effector of Ras-associated binding proteins Rab3A and Rab27A. Noc2 contains an N-terminal Rab3A effector domain which harbors a conserved zinc finger, but lacks tandem C2 domains []. |
