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Protein Domain : SNF1-related protein kinase regulatory subunit beta-1

Primary Identifier  IPR037170 Type  Family
Short Name  KINB1
description  This family represents the regulatory beta-1 subunit of the plant SNF1-related protein kinase (SnRK) complex, probably a trimeric complex consisting of an alpha catalytic subunit, and a beta and a gamma non-catalytic regulatory subunits []. In Arabidopsis, there are two isoforms of the catalytic subunit (AKIN10 and AKIN11), three beta subunits (AKINbeta1, AKINbeta2, and AKINbeta3) and one gamma subunit (AKINg) [, ]. The SnRK complex in higher plants plays a role in signal transduction cascades regulating gene expression, carbohydrate and nitrogen metabolism []. Some known SnRK1 substrates are key metabolic enzymes such as sucrose phosphate synthase, nitrate reductase, and HMG-CoA reductase [], while others are transcription factors []. Its physical interaction with nitrate reductase specifically occurs via the AKINbeta1 subunit [].Beta subunits show conserved domains in different organisms. These domains include the Association with the SNF1 Complex (ASC)domain, which is important for interaction with the alpha and gamma subunits, and a specialised carbohydrate-binding module named the Glycogen Binding Domain (GBD). In Arabidopsis, only AKINbeta1 and AKINbeta2 exhibit both the GBD and the ASC domains [, ]. AKINbeta3 could be a plant specific subunit [].

0 Child Features

1 Parent Features

0 Protein Domain Regions