| Primary Identifier | IPR043545 | Type | Family |
| Short Name | GRIP1/2 |
| description | Glutamate receptor-interacting proteins (GRIPs) are multi-PDZ domain scaffolding proteins required for dendrite development. There are two members of the GRIP family: GRIP1 and GRIP2/ABP (AMPA receptor binding protein) []. GRIPs regulate AMPAR receptor trafficking and neuronal plasticity [, ]. They also bind various receptor and signalling proteins, such as EphB receptors, ephrinB ligands, the proteoglycan NG2, the Fraser syndrome protein Fras1, and matrix metalloproteinase 5 [].This entry includes glutamate receptor-interacting protein 1/2 (GRIP1/2). |
