| Primary Identifier | IPR043533 | Type | Family |
| Short Name | CNBD1/2 |
| description | Cyclic nucleotide-binding proteins play a prominent role in cellular signaling. Their activity is regulated by binding of cAMP and/or cGMP to a highly conserved cyclic nucleotide-binding domain (CNBD), consisting of eight beta sheets that are flanked by three alpha helices []. This entry includes cyclic nucleotide-binding domain-containing protein 1/2 (CNBD1/2). Mouse CNBD2, also known as CRIS, plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm []. |
