Primary Identifier | IPR006634 | Type | Domain |
Short Name | TLC-dom |
description | TLC is a protein domain with at least 5 transmembrane α-helices. Lag1p and Lac1pare essential foracyl-CoA-dependent ceramide synthesis [], TRAM is a subunitof the translocon and the CLN8gene is mutated in Northern epilepsy syndrome. Proteins containing this domain may possessmultiple functions such aslipid trafficking, metabolism, or sensing. Trh homologues possess additionalhomeobox domains []. |