| Primary Identifier | IPR006616 | Type | Repeat |
| Short Name | DM9_repeat |
| description | This repeat of unknown function was identified in Diptera proteins; later on, it was also found in a wide range of invertebrates and vertebrates [], such as natterin [, ]. It is often present in proteins comprising only two or four DM9 repeats and occasionally is linked to other domains at its N- or C-terminal. In the mannose-specific lectin CGL1 from Crassostrea gigas, DM9 exhibit high binding specificity and avidity toward D-mannose residue and served as a pattern recognition receptor (PRR) with a broad range of recognition spectrum to various pathogen-associated molecular patterns []. It also mediates immune recognition and cellular encapsulation []. |
