Primary Identifier | IPR006669 | Type | Family |
Short Name | MgtE_transporter |
description | This entry represents the MgtE family of magnesium transporters. MgtE is a highly Mg2+-selective channel gated by Mg2+ []. It is an SLC41A1 orthologue found in prokaryotes, which consists of a homodimer architecture with five transmembrane domains in the C terminus and cytosolic N terminus domains. Structural and functional analyses showed MgtE conserved acidic side-chains play a key role as part of its selectivity filter. Proteins in this family contains two highly conserved aspartates that may be involved in cation binding [, , , ]. |