| Primary Identifier | IPR004018 | Type | Repeat |
| Short Name | RPEL_repeat |
| description | RPEL repeat (RPxxxEL) containing proteins are found in a wide range ofmetazoan organisms. RPEL repeats have been shown to be required forunpolymerised actin binding and proteins containing RPEL repeats are able tomodify cell shape and/or are important in the regulation of gene expression bythe actin cytoskeleton. RPEL repeats can be found in association with the SAPmotif, which could be involved in DNA binding [, ].Some proteins known to containRPEL repeats are listed below:Mammalian myocardin, heart-specific serum response factor (SRF) co-activator.Vertebrate myocardin-related transcription factor A (MRTF-A or MAL), asignal-regulated SRF co-activator.Vertebrate myocardin-related transcription factor B (MRTF-B).Mammalian phosphatase and actin regulator 1 to 3. |
