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Protein Domain : GDNF/GAS1

Primary Identifier  IPR016017 Type  Domain
Short Name  GDNF/GAS1
description  This cysteine rich domain is found in multiple copies in GNDF and GAS1 proteins. GDNF and neurturin (NTN) receptors are potent survival factors for sympathetic, sensory and central nervous system neurons [, ]. GDNF and neurturin promote neuronal survival by signalling through similar multicomponent receptors that consist of a common receptor tyrosine kinase and a member of a GPI-linked family of receptors that determines ligand specificity [].

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88 Protein Domain Regions