Primary Identifier | IPR028273 | Type | Family |
Short Name | Myozap |
description | Myocardial zonula adherens protein (Myozap) plays a role in cellular signaling via Rho-related GTP-binding proteins and activation of transcription factor SRF []. It localises to the intercalated disk in cardiomyocytes and colocalises with GRIN1 in postsynaptic neurites [, ]. It also colocalises with cortical actin at the intercalated disc in the cardiomyocytes []. In cortical neurons, it may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 []. |