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Protein Domain : Myocardial zonula adherens protein

Primary Identifier  IPR028273 Type  Family
Short Name  Myozap
description  Myocardial zonula adherens protein (Myozap) plays a role in cellular signaling via Rho-related GTP-binding proteins and activation of transcription factor SRF []. It localises to the intercalated disk in cardiomyocytes and colocalises with GRIN1 in postsynaptic neurites [, ]. It also colocalises with cortical actin at the intercalated disc in the cardiomyocytes []. In cortical neurons, it may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 [].

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5 Protein Domain Regions