Primary Identifier | IPR028278 | Type | Family |
Short Name | MRI |
description | CYREN is a cell-cycle-specific inhibitor of classical non-homologous end joining (cNHEJ) that promotes error-free repair by homologous recombination during the S and G2 phases (when sister chromatids are present) []. It was originally known as MRI (modulator of retrovirus infection), as it was isolated as a gene that could reverse the resistance to retroviral infection in a mutant cell line []. |