| Primary Identifier | IPR004338 | Type | Family |
| Short Name | NqrB/RnfD |
| description | This family of proteins describes the Nqr2 (NqrB) subunit of the bacterial 6-subunit sodium-translocating NADH-ubiquinone oxidoreductase (i.e. a respiration linked sodium pump). In Vibrio cholerae, it negatively regulates the expression of virulence factors through inhibiting (by an unknown mechanism) the transcription of the transcriptional activator ToxT [].The family also includes RnfD, which is a subunit of the Rnf complex, a ferredoxin:NAD+ oxidoreductase that appears to translocate different ions (protons or sodium) in different bacteria []. The similarity of RnfD to NADH-ubiquinone oxidoreductases was previously noted []. |
