| Primary Identifier | IPR045072 | Type | Family |
| Short Name | MKRN-like |
| description | The MKRN protein family includes the ribonucleoproteins that are characterised by a variety of zinc-finger motifs, including typical arrays of one to four C3H1-type zinc fingers and a C3HC4-type RING-HC finger. Another motif rich in Cys and His residues (CH), with so far unknown function, is also generally present in MKRN proteins. MKRN proteins may have E3 ubiquitin ligase activity [, ]. At least four makorin genes exist in vertebrates [].Makorin 3 was first identified in the Prader-Willi syndrome critical region in the human genome, but has no obvious role in the disease []. |
