Primary Identifier | IPR016376 | Type | Family |
Short Name | GCN5/PCAF |
description | Eukaryotic GCN5 acetyltransferases influence diverse biological processes by acetylating histones and non-histone proteins and regulating chromatin and gene-specific transcription as part of multiprotein complexes. Vertebrate organisms, express two paralogous GCN5-like acetyltransferases, GCN5 and PCAF (also known as KAT2A and KAT2B), which is included in this entry []. GCN5/PCAF is a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 [, ]. |