| Primary Identifier | IPR028156 | Type | Family |
| Short Name | RIP |
| description | This entry represents the replication protein A (RPA) interacting protein. RPA is a single stranded DNA-binding protein involved in DNA replication, repair, and recombination []. After synthesis in thecytoplasm, RPA is transported into the nucleus mediated by RPA interacting protein [, ]. In humans, RPA interacting protein has several splice isoforms, including hRIPalpha, hRIPbeta, hRIPgamma, hRIPdelta1, hRIPdelta2, and hRIPdelta3. hRIPbeta transports RPA into the PML nuclear body and releases RPA upon UV irradiation []. It seems that the number of splice isoforms of RIPalpha is species-specific and has a tendency to increase in higher eukaryotes []. |
