| Primary Identifier | IPR006849 | Type | Family |
| Short Name | Elp1 |
| description | Elongator complex protein 1 (also known as Iki3) is a component of the RNA polymerase II elongator complex, which is a major histone acetyltransferase component of the RNA polymerase II (RNAPII) holoenzyme. The eukaryotic elongator complex has been associated with many cellular activities, including transcriptional elongation [, ], but its main function is tRNA modification [, ]. It is required for the formation of 5-methoxy-carbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups on uridine nucleosides present at the wobble position of many tRNAs []. |
